Iodine Treats Breast Cancer,
Regression of Breast Cancer after Iodine Supplementation
In his Iodine book, David Brownstein MD reports
three cases of spontaneous regression of breast cancer after iodine
Left Image: Surgeons performing a breast biopsy courtesy of the NIH,
and wikimedia commons.
The first patient
was a 63 year old English teacher. She
was diagnosed with breast cancer in 1989 and after declining conventional treatment,
took 50 mg per day of Iodoral, (Iodine). Six weeks later, a PET scan showed
"all of the existing tumors were
patient was a 73 year old Delores. She
was diagnosed with breast cancer in 2003, declined conventional treatment with
radiation and chemotherapy, and instead, Dolores took 50 mg of Iodoral daily. A
follow up ultrasound of the breast 18 months later showed," It appears that these malignancies have
diminished in size since the last examination. Interval improvement is
definitely seen". Two years
later, a follow up mammogram and ultrasound failed to show any abnormality and
were read by the radiologist as normal.
The third patient was 52 year old Joyce.
She was diagnosed with breast cancer two years prior, and started on
Iodoral 50 mg per day. Three years after
starting Iodoral, her follow up mammograms and ultrasound exams show decreasing
size of the tumor with no progression.(1)
Deficiency Causes Breast Cancer - The Overwhelming Evidence
Studies of Dietary Iodine Intake
Iodine deficiency is associated with a higher rate
of goiter and breast cancer. Similarly,
higher dietary Iodine intake is associated with less goiter and breast
cancer. For example, Japan has the
highest dietary intake of iodine (several milligrams per day), and the lowest
rates for goiter and breast cancer. However, when Japanese women immigrate and
change dietary intake of Iodine to the lower 150 mcg/day in America, breast
cancer rates increase.(1) Iceland is
another country with high Iodine intake and low rates for goiter and breast
cancer. The high dietary iodine came
from the fishing industry before World War One.
In those days, the fish meal was fed to dairy cows providing milk with
high iodine content. After World War One,
the fish meal was eliminated from the dairy cows, and breast cancer rates soared
ten-fold. (2) Iodine deficient diets in animals induces breast cancer and
Iodine supplementation is safe, and useful
for prevention and treatment of breast cancer.
Iodine Research from Mexico, India and Japan.
The Shrivastava group in India reported molecular
iodine induces apoptosis (programmed cell death) in human breast cancer cell
cultures. "Iodine showed cytotoxic effects in the cultured human breast cancer
cells". (3) From Mexico, the Carmen Aceves Velasco Group reported
Iodine to be safe, with no harmful effects on thyroid function, and an
anti-proliferative effect on human breast cancer cell cultures. (5-7) Their 2009 paper reported the mechanism by
which Iodine works as an anti-cancer agent.
Iodine binds to membrane lipids called lactones forming iodo-lactones
which regulate apoptosis (programmed cell death). Iodine causes apoptosis which makes cancer
cells undergo programmed cell death.(4) Dr. Aceves concluded that continuous
molecular iodine treatment has a "potent
antineoplastic effect" on the progression of mammary cancer. (10) From Japan, Dr Funahashi reported a common
seaweed food containing high iodine content is more beneficial than
chemotherapy on breast cancer .
"He found that administration of Lugol’s iodine or iodine-rich
Wakame seaweed to rats treated with the carcinogen dimethyl benzanthracene
suppressed the development of mammary tumors. The same group demonstrated that
seaweed induced apoptosis in human breast cancer cells with greater potency
than that of fluorouracil, a chemotherapeutic agent used to treat breast
A 2008 paper by Bernard A. Eskin MD showed that
Iodine actually altered gene expression in breast cancer cells, inducing
programmed cell death. (9) A 2003 study
by Ling Zhang showed that molecular Iodine caused lung cancer cells to undergo
programmed cell death (apoptosis). These
lung cancer cells had been genetically modified to increase iodine
uptake.(12) Interestingly, a 1993 case
report describes spontaneous remission of lung cancer in a patient incidentally
treated with Amiodorone which contains iodine (about 9 mg per day)(13)
Conclusion: Current Iodine research calls for use of
molecular Iodine for all patients with breast cancer. (10-11) Other cancers such as lung and prostate may
also benefit. Further research on Iodine
as cancer chemotherapy should receive top priority for NIH funding. Iodine in the form of Iodoral tablets is
available OTC, on the internet without a prescription.
Disclosure: The author has no financial interest in
the Iodine Book mentioned above, or in any company that manufactures Iodine
For references and links, see my web site: www.bioidenticalhormones101.com
Articles With Related Interest
Iodine Prevent Breast Cancer Part One
Iodine Prevents Breast Cancer Part Two
Iodine Use in Graves Disease
References for Chapter 23. Iodine
Treats Breast Cancer, Overwhelming Evidence
(1) Iodine, Why You
Need It , Why You Can't Live Without It, by David Brownstein MD
Fourth Edition 2009, Medical Alternatives Press.
(2) Breast Cancer and
Iodine by David M Derry MD PhD 2001 Trafford.
(3) http://www.jbc.org/content/281/28/19762.abstract July 14, 2006 The Journal
of Biological Chemistry, 281, 19762-19771 Molecular Iodine Induces
Caspase-independent Apoptosis in Human Breast Carcinoma Cells Involving the
Mitochondria-mediated Pathway. Ashutosh Shrivastava et al.
Mol Cancer. 2009; 8: 33. Published online 2009 June 6. Antineoplastic effect of
iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome
proliferator-activated receptors (PPAR). Carmen Aceves et al.
THYROID Volume 17, Number 9, 2007. Uptake and Gene Expression with
Antitumoral Doses of Iodine in Thyroid and Mammary Gland: Evidence That Chronic
Administration Has No Harmful Effects. Carmen Aceves Velasco et al.
(6) http://erc.endocrinology-journals.org/cgi/content/full/13/4/1147 Endocr Relat Cancer. 2006 Dec; 13 (4): 1147-58. Uptake and
antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell
line. C Aceves et al. Querétaro, México.
(7) http://erc.endocrinology-journals.org/cgi/content/abstract/15/4/1003 Signaling pathways involved in
the antiproliferative effect of molecular iodine in normal and tumoral breast
cells: evidence that 6-iodolactone mediates apoptotic effects. C Aceves et
al. Querétaro México.
RAPID COMMUNICATION Jpn. J. Cancer Res. 92, 483–487, May 2001 Seaweed Prevents Breast Cancer? Hiroomi
Funahashi et al. Japan.
(9) http://www.medsci.org/v05p0189 Int J Med Sci 2008; 5:189-196 .
Iodine Alters Gene Expression in the MCF7 Breast Cancer Cell Line: Evidence for
an Anti-Estrogen Effect of Iodine. Frederick R. Stoddard II1 et al.
Research Calls for Use of Molecular Iodine to Treat Breast Cancer. Market Wire,
Cancer Causes and Control 11: 121±127, 2000. Kluwer Academic Publishers.
Hypothesis: Iodine, selenium and the development of breast cancer. Stephen A.
Cann , Johannes P. van Netten Christiaan van Netten.
Cancer research 2003;63(16):5065-72.
Effectively Induces Apoptosis in Genetically Modified Lung Cancer Cells1
Ling Zhang et al.
J Natl Cancer Inst. 1993 Aug 18;85(16):1342-3. Spontaneous remission of
metastatic lung cancer following myxedema coma--an apoptosis-related
phenomenon? Hercbergs A, Leith JT.
2000 Nature America Inc. The mammary gland iodide transporter is expressed during
lactation and in breast cancer. Uygar H. Tazebay et al.
(15) http://web.tiscali.it/iodio/ Dr. Sebastiano Venturi
investigator on Iodine Deficiency Disorders and Iodine metabolism
(16) http://web.tiscali.it/iodio/ Is there a role for iodine in
breast diseases? S. Venturi
The Effect of Supraphysiologic Levels of Iodine on Patients with Cyclic Mastalgia, Jack H.
http://www.biomedcentral.com/content/pdf/bcr638.pdf The thyroid, iodine and breast
cancer by Peter PA Smyth, Breast Cancer Res 2003, 5:235-238
(19) http://www.ncbi.nlm.nih.gov/pubmed/8221402 Can J Surg. 1993
Oct;36(5):453-60. Iodine replacement in fibrocystic disease of the breast. Ghent
WR, Eskin BA, Low DA, Hill LP. Department of Surgery, Queen's University, Hotel
Dieu Hospital, Kingston, Ont.
(20) http://www.optimox.com/pics/Iodine/opt_Research_I.shtml Guy Abraham Iodine Project
(21) http://cypress.he.net/~bigmacnc/drflechas/index.htm George Flechas MD
(22) https://www.drbrownstein.com/bookstore_Iodine.php David Brownstein MD Iodine Book
(23) http://www.ei-resource.org/expert-columns/dr.-jacob-teitelbaums-column/iodine-deficiency-%11-an-old-epidemic-is-back/ Jacob Teitelbaum MD on Iodine
(24) http://www.jpands.org/vol11no4/millerd.pdf Extrathyroidal Benefits of
Iodine by Donald W. Miller, Jr., M.D. Journal of American Physicians and Surgeons
Volume 11 Number 4 Winter 2006.
(25) http://www.breastcancerchoices.org/iodineref2.html Investigating the Relationship
Between Iodine and the Breast Part 2: What Are Iodine's Mechanisms of Action?
Observations and Theories. Breast Cancer Choices.
Part 3: What is the Effect of Iodine on Breast Cancer? Breast Cancer Choices.
Iodine and the Breast, Iodine for Health.
(28) http://www.hacres.com/diet/articles/Iodine.pdf Recent Advances in Iodine
Nutrition by Michael Donaldson, PhD
(29) http://www.thorne.com/altmedrev/.fulltext/13/2/116.pdf Iodine: Deficiency and
Therapeutic Considerations Lyn Patrick, ND Alternative Medicine Review Volume
13, Number 2 2008
In vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts after
MUC1-Driven Expression of the Sodium Iodide Symporter. Roisin M. Dwyer et
al. Clin Cancer Res February 15, 2005 11; 1483.
Jeffrey Dach MD
7450 Griffin Road Suite 190
Davie, Florida 33314
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