The Importance of
What is a Bioidentical Hormone, and How Do They Differ From Synthetic Hormones?
First of all, let us look at the definition and
meaning of “bioidentical hormones”. How
do bioidentical hormones differ from the synthetic hormones offered by the
mainstream medical system? Bioidentical
hormones are the hormones that exist in the human body naturally. Synthetic hormones are these very same human
hormones that are chemically altered. Here, we are referring to the chemical
structure of the molecule. Bioidentical
hormones have the naturally occurring chemical structure, so it cannot be
patented. Synthetic hormones have been
chemically altered so they CAN BE patented. This is the key distinction.
Chemically Alter a Human Hormone?
You might ask, “Why Chemically Alter a Human
Hormone”? This is done in order to
obtain a patent. The drug company hires
chemists to alter the structure of human hormones in the laboratory so the drug
company can obtain a patent on the new chemical structure, which is a new
drug. The patent grants exclusive
marketing rights to the drug company, and is necessary to protect profits. Because of a quirk in our patent laws, only
chemically altered substances can be patented.
Natural substances like human hormones cannot be patented, and are
therefore generally not profitable to manufacture.
Chemically Altered Hormones are Monster
The reality is that it is not a good idea to alter
the chemical structure of a human hormone. Hormones fit onto their receptors
just like a "lock and key", so any slight alteration of their
chemical structure creates a "monster hormone" with unintended
effects. These resulting "monster
hormones" are never found in the human body or anywhere else in
nature. The reality is that these synthetically
altered monster hormones should never have been approved for marketing and sale
to the American People, and yet that is exactly what your mainstream medical
doctor will offer you if you ask for hormones.
do we use the word bio-identical to describe natural human hormones?
You are probably wondering why we use the word,
"bioidentical"? That's an
excellent question. I can remember back
when I was in first year medical school learning biochemistry at the University
of Illinois in Chicago. Our class used
Lehninger's classic textbook of biochemistry which is still in use today.(5) Dr. Lehninger never uses the word, “bio-identical
hormones”, because all human hormones are by definition, “bioidentical hormones”. Dr Lehninger’s biochemistry book simply used
the word, "hormone". Using a
word like "bioidentical" was simply redundant and unnecessary for biochemistry
textbooks, as it should be today.
Hormones are chemically altered versions of natural human hormones. This alteration
is required in order to obtain a patent.
However, this chemical alteration creates a “monster” which causes
cancer and heart disease.
The Medical Information War and Terminology
Years ago, after the invention of synthetic monster
hormones, an information war was launched by the drug industry creating
confusion in the public and even among medical professionals about the
difference between natural human hormones and synthetic monster hormones. Because of this medical information war, we
must use the terminology, "bioidentical hormones”, which really means
human hormones, in order to differentiate them from synthetic hormones. In reality, it is an embarrassment to
medical science that we use the word "bio-identical" for natural
hormones found in the human body. We
shouldn't feel that we are forced to do this.
It should be sufficient to use the same old names in the biochemistry
text books. The simple word
“hormone" should suffice. Yet here
we are again finding ourselves using the word "bio-identical hormone"
thanks to the "Information War" going on between natural medicine and
the drug industry.
do Hormones Work? They Turn on Protein
Hormones are messengers that attach directly to the
DNA of trillions of our cells and influence gene expression. Once bound to the DNA, the hormone messenger
turns on DNA expression of protein synthesis.
DNA contains the source code for the manufacture of proteins. The Hormone is a messenger that tells the DNA
to produce these proteins. You might
ask, “Why Are Proteins Important ?”
Proteins are the major building block for the human body, and all life
for that matter. Proteins serve a
variety of functions. For example,
"structural" proteins make up the structural elements of the body
such as bones, skin, arteries, hair, connective tissue, ligaments, tendons,
muscles. Other proteins called enzymes
are involved in energy production. There
are proteins involved in communication, neurological function, and cognition
called neurotransmitters. There are
proteins involved in the immune system called antibodies, and the list goes
on. The various types of proteins are
used to make the cells in every organ in the body.
and Reparative Proteins
We need a constant supply of proteins to repair the
body's wear and tear. A marathon runner,
for example, suffers wear and tear on the tendons, ligaments and muscles used
in the marathon run. Recovery time after
a marathon depends on the speed of repair of these injuries. During recovery, new proteins and new cells
are manufactured and used for repair.
life, including ours, is based on the ability to regenerate new cell layers
made of proteins. Protein production, in turn, is controlled by DNA in the
cell nucleus. Hormones attach to
receptors on the DNA and control protein production. Low hormone levels mean low protein
production and reduced ability to repair and regenerate tissues.
New Cell Layers Are Needed for Life
In order to live, we need to make new cells. As our older cells and cell layers age and
eventually die, we must have the ability to manufacture new cells. Examples are blood cells that must be
replaced by the bone marrow every 90 days, the skin cells that slough off as
the outer layer to be replaced by new layers of cells underneath. The gastrointestinal lining is generated at
the basal cell layer. These basal cells
mature as they migrate to the surface where they eventually live out their life
span, die and slough off. All organ
systems in our body require new cells to replace old ones. These new cells are made of proteins, so
regeneration of new cell layers requires the DNA to be "turned on" to
make these new proteins and cells.
Levels Decline with Age
We know from observational studies that hormones
levels decline with age. Starting around
age 50, the abrupt hormone decline in women is called menopause with cessation
of ovulation. In men, hormonal decline
after age 50 is called Andropause, with a gradual decline in testosterone
in Human Life Span
Starting around the year 1820, which marks the beginning
of the Industrial Revolution, there has been an increase in the human life
span.(1) I suspect this is due to
improved living standards, mass production of goods and services, and better nutrition. Before 1900, most people did not live past
50 years, so hormonal decline was not an really an issue in the population. However, after the year 1900, people are living
beyond the age of 50, with the onset of hormonal decline called menopause in
women, and andropause in men. This trend
has increased to the point that we now have more people over fifty than ever
before, creating a huge population of people with hormonal decline.
of Reparative Proteins Leads to Degenerative Diseases of Aging
Without this hormone message which turns on DNA
expression of protein synthesis, we lack the reparative and regenerative
proteins needed to prevent the degenerative diseases of aging. A Natural Medicine approach provides
bioidentical hormone replacement which prevents (and in some cases reverses)
these degenerative diseases of aging.
Here is a list with the mainstream drug treatment offered.
List of the
Disease Means Great Profits for Drug Companies
The major drug companies make most of their profits
on blockbuster drugs aimed at one of the above degenerative diseases of
aging. Since all of these degenerative
diseases are directly caused by hormonal decline, they can be prevented or
reversed (at least partially reversed) with the use of bio-identical hormones,
representing direct economic competition with the drug industry which sells a
drug for each degenerative disease (see above chart).
Hormones prevent or reverse the degenerative diseases of aging , directly
competing with the profits of the drug industry, thereby explaining the
animosity and information warfare between the drug industry and bioidentical
Natural Medicine Means Lost Profits for the Drug Industry
If bio-identical hormones were widely used, this
would mean massive lost sales and lost profits for the drug industry. It is not difficult to understand why there
is animosity and competition between the drug industry and natural medicine,
and especially between the drug industry and natural bioidentical hormones,
with a raging medical information war going on.
For references and links, see my web site: www.bioidenticalhormones101.com
Articles with Related interest:
Bioidentical Homrones Prevent Osteoarthritis
Bioidentical Hormones Prevent Heart Disease
The Importance of Bioidentical Hormones
The Importance of the Pelvic Sonogram
The Safety of Bioidentical Hormones
for Chapter 9. The Importance of BioIdentical Hormones
(1) http://www.demogr.mpg.de/publications/files/brokenlimits.htm Broken Limits to Life Expectancy
Jim Oeppen and James W.Vaupel. also see:
(2) http://www.postgradmed.com/index.php?article=1949 Postgraduate Medicine: Volume
121: No.1 January 2009. The Bioidentical Hormone Debate:Are Bioidentical
Hormones (Estradiol, Estriol, and Progesterone) Safer or More Efficacious than
Commonly Used Synthetic Versions in Hormone Replacement Therapy?Kent Holtorf,
(3) http://online.wsj.com/article/SB123717056802137143.html March 16, 2009 The Truth About
Hormone Therapy Wall Street Journal by Erika Schwartz , Kent Holtorf , and David
Care. 2008 Dec;35(4):669-705. Hormones in wellness and disease prevention:
common practices, current state of the evidence, and questions for the future.
By Schwartz ET, Holtorf K.
(5) Lehninger Principles of Biochemistry by Albert Lehninger, David L. Nelson,
Michael M. Cox. W. H. Freeman; Fifth
Edition edition (June 15, 2008)
Author: Jeffrey Dach MD
Jeffrey Dach MD
7450 Griffin Road Suite 190
Davie, Florida 33314
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